Promethazine Promethazine is usually a phenothiazine spinoff, which differs structurally from your antipsychotic phenothiazines because of the presence of a branched aspect chain and no ring substitution.

Most MAO inhibitors also needs to not be taken for 2 months just before treatment using this medication. Question your health practitioner when to get started on or prevent using this medication.

Unresponsive Cough The dosage of Promethazine HCl and Codeine Phosphate Oral Solution should not be increased if cough fails to respond; an unresponsive cough really should be reevaluated in 5 times or sooner for attainable fundamental pathology, like foreign system or lessen respiratory tract illness [see Dosage and Administration (two.3)].

As a result of danger of respiratory depression, prevent the usage of opioid antitussives, which includes Promethazine HCl and Codeine Phosphate Oral Remedy in sufferers with compromised respiratory operate, clients susceptible to respiratory failure, and in elderly, cachectic, or debilitated sufferers.

When utilized for an extended time, this medication may not operate likewise and may require diverse dosing. Speak with your physician if this medication stops Functioning nicely.

The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers below six decades of age. Concomitant administration of promethazine products with other respiratory depressants has an Affiliation with respiratory despair, and at times Dying, in pediatric patients. The Promethazine codeine syrup association does not directly relate to individualized pounds-dependent dosing, which might if not permit Safe and sound administration.

Neuroleptic malignant syndrome (NMS) which may lead to death. Inform you Health care service provider without delay When you've got any of the next indications of NMS:

Promethazine Carcinogenicity studies were performed with promethazine hydrochloride. Two-calendar year studies in F344/N rats and B6C3F1 mice were conducted to evaluate the carcinogenic prospective of promethazine hydrochloride. No proof of tumorigenicity was noticed in male and feminine rats at promethazine hydrochloride oral doses nearly 33 mg/kg/day for five times/week (roughly akin to ten periods the MRHD on a mg/m2 foundation).

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Give your treatment team an index of all medications you utilize. They can inform you the amount of medication to acquire. Never get more medication than directed. Get emergency support right away Should you have difficulties breathing.

Promethazine is usually a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines via the existence of the branched aspect chain and no ring substitution.

We anticipate reposting the images when we're able establish and filter out illustrations or photos that don't match the data furnished within the drug labels. NDC Codes

This drug may perhaps cause you to dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you much more dizzy or drowsy. Tend not to travel, use equipment, or do just about anything that demands alertness or apparent eyesight until finally you can do it properly.

Drug interactions may perhaps adjust how your drugs work or improve your threat for severe Unwanted side effects. This doc won't contain all feasible drug interactions.